State health officials investigate Salmonella illnesses in Bethel area

first_imgThe Alaska Division of Public Health is investigating salmonella infections in the Bethel area. A team is in Bethel to track down the source of the infection.Listen nowMedical illustration of non-typhoidal salmonella. (Courtesy of the Center for Disease Control)Louisa Castrodale is an epidemiologist with the state’s Public Health division.“It’s not even the end of July and we had gotten about six cases of confirmed salmonella from the Bethel-YK area,” Castrodale said. “That’s a large number of cases for a short amount of time in a smaller location, so we were really concerned there was a common source for these infections.”Salmonella symptoms include diarrhea, stomach-ache, vomiting, fever, headache, and dehydration, especially in infants. Symptoms can start showing between six to 72 hours after exposure to salmonella bacteria, and the illness can last four to seven days.Castrodale said a team of three people from the state health department arrived in Bethel Wednesday and will stay until Friday to try and find a possible source for the illnesses.“Could have either a contaminated food product, so a food product that had salmonella in it, or you could have contact with a person that had salmonella,” Castrodale said.Salmonella can also be contracted through touching pets or animals, by not washing one’s hands, by drinking water or milk with the bacteria in it, or by eating foods that don’t have to be cooked, but that came into contact with the bacteria. Salmonella bacteria do not usually affect the taste or smell of foods.Over 50 salmonella cases are confirmed in Alaska each year; the illness is diagnosed by getting a stool sample to identify the bacteria.last_img read more

Antibiotics 20 The atomic structure and mechanism of mammalian hostdefense peptides

first_imgCrystal structure and surface characteristics of the human dermcidin channel. (A) X-ray structure of the hexameric DCD channel shown in cartoon representation from the side and top (Middle and Right), and as surface representation (Left). The different orientations of the individual peptides relative to the membrane normal are marked in orange and dark blue, and termini are marked (NT, N terminus; CT, C terminus). Arrows combined with tilt angle and axes give the relative orientation. Residues involved in Zn binding are shown in stick representation and Zn ions are marked in gray. The symmetry axis of the channel is marked with C2 (for the side view) and C3 (for the top view). Two interfaces of different surface area are formed after trimerization and named IF1 and IF2. (B) Close-up into the Zn-binding site S1. Four residues (Glu5 and Asp11 from one peptide and Asp41 and His38 from the second) form each Zn-binding site. The distance between the Zn ions is marked by arrows. (C) Electrostatic surface representation of the channel with two monomers marked in ribbon representation. The channel comprises five alternating patches of elongated negative (red) and ring-like positive (blue) charge. (D) Side view of DCD (hydrophobic residues in magenta). (E) Ribbon model of DCD. The pore diameter is represented by spheres. The lateral entry points are marked with circles. (F) Hydrophilic residues on the trimeric interface (negatively charged residues in red, positively charged residues in blue, polar residues in green). Nonpolar residues are shown in white. (G) The hydrophilic channel interior. For clarity, the front dimer is omitted; colors as in F. (H) Channel radius along the pore axis. Copyright © PNAS, doi:10.1073/pnas.1214739110 Frogs skin gives researchers the hop on bacteria ( —While the natural world is replete with compounds that form the basis of many disease-fighting pharmaceuticals, it is also the case that humans and other mammals produce their own host-defense peptide-derived broad-spectrum antibiotics to combat bacterial and fungal infections. By attacking microbial cell membranes, these peptides prevent bacteria from developing rapid antibiotic resistance. While over 1,700 of these peptides are known, the structural and mechanical aspects of their functional activity have remained an unanswered question. Recently, however, scientists at Max Planck Institute for Biophysical Chemistry, Max Planck Institute for Developmental Biology, The University of Edinburgh, and other instiutions1 determined the X-ray crystal structure as well as solid-state nuclear magnetic resonance (NMR) spectroscopy, electrophysiology, and molecular dynamic (MD) simulations of human dermcidin (DCD), revealing its mechanism at atomic scale. The researchers conclude that their results may lead to the peptide structure-based design of second-generation antibiotics. PausePlay% buffered00:0000:00UnmuteMuteDisable captionsEnable captionsSettingsCaptionsDisabledQuality0SpeedNormalCaptionsGo back to previous menuQualityGo back to previous menuSpeedGo back to previous menu0.5×0.75×Normal1.25×1.5×1.75×2×Exit fullscreenEnter fullscreen , Nature Prof. Kornelius Zeth spoke with about the challenges that he, Dr. Ulrich Zachariae, Dr. Chen Song, Dr. Bert de Groot, and his other colleagues encountered in conducted their research. “For crystallography it was very difficult to find a proper peptide source. In fact, we had to use five different peptides from different companies until we found a company, Peptide 2.0 Inc., which produced the peptide in the correct way,” Zeth recalls. “However, I can’t say they’ve modified their process – and luck also a factor, as are and several parameters which are influential aside from the peptide, such as who conducts the robotic screening, local climate and so on.”Moreover, the simulations that revealed the antibiotic mechanism of human dermcidin had their own complications. “Simulations require time and experience in order to capture the correct lipidic environment,” Zeth adds. “Also, the choice of the proper MD method was critical to tracing the mechanism by which ions passed through the channel.” The simulations went on for many months, he illustrates, depending on the system studied, to get a complete picture of the membrane channels. More specifically, Song notes that the production simulations took more than a year – roughly 650 days – in real time using 48 CPUs.”Several consistency checks were carried out to ensure the validity of the MD simulations,” de Groot points out. “First, the simulation parameters and setup were carefully selected to mimic the bacterial conditions as closely as possible. Second, to ensure convergence the simulations were carried out multiple times, from different starting conditions. Third, the conductance derived from the electrophysiology simulations were directly compared to measured values, showing quantitative agreement.”Another challenge, Zeth says, was conducting electrophysiology experiments in which the scientists characterized the activity of dermcidin in membranes under various conditions. “Methods applied to solve this problem are typically based on recent developments in electrophysiology. One general problem of DCD is that the peptide is very soluble in water and does not easily enter artificial membranes.” in fact, this finding has also caused NMR problems when trying to verify the tilting of the channel in membranes as predicted by MD simulations. These studies were hampered by the small portion of the peptide that was observable in an integral membrane conformation. More information: Crystal structure and functional mechanism of a human antimicrobial membrane channel, PNAS March 19, 2013 vol. 110 no. 12 4586-4591, doi:10.1073/pnas.1214739110Related: 1Georg August University – Göttingen, University of Strasbourg, Centre National de la Recherche Scientifique, Freiburg University, University of Basque Country, Spanish Science Research Council 2Editor’s Summary: Trigger for psoriasis, Nature 4 October 2007 Discussing how their findings articulate the comprehensive mechanism for the membrane-disruptive action of this mammalian host-defense peptide at atomistic level, Zeth notes that their findings are based on the combination of several techniques. “Starting from the crystal structure,” he explains, “we modeled the ion flux, later deciding to verify the theoretical calculations and values by experimental data. We’ve also tried to model the tilting behavior seen in MD simulation by solid state NMR techniques, but this approach failed. Nevertheless, the overall picture, while incomplete, leads to many follow-up experiments and stimulates the AMP community regarding the development of new mechanistic views.” As for the conductance calculated by MD, however, researchers we were able to reproduce these values using planar lipid membrane techniques in an error range of only 20%. While their paper states that their results may form a foundation for the structure-based design of peptide antibiotics, Zeth says that this is rather difficult to judge. “In fact, he says, the German company BRAIN is trying to introduce DCD into pharmaceutical studies. However, if you look closer into the general applications of peptides as AMPs, it’s rather frustrating. To my knowledge,” Zeth acknowledges, “there are no AMP peptides sold as pharmaceuticals at the moment, although the general market of peptides – against cancer and other diseases – is still growing. The problem is the size and stability of the peptides if given orally or into the bloodstream as proteases, but. DCD is active on skin – so might be easier if it was to be introduced into creams.”Zeth then described medical properties and potential of host-defense antimicrobial peptides for comparison with traditional small-molecule antibiotics.Specificity: Rather unspecific. Gram-positives and negatives are concerned while with traditional antibiotics either Gram+/Gram- are treated.Efficacy: likely to be more efficient due to inherent molecular antibacterial propertiesSafety: Not yet determined but as these molecules come from humans they should not be toxicPost-xenotransplantation immune response: Currently unknown. The problem with antimicrobial peptides is protease-based instability in the bloodstream and stomach.Autoimmune diseases: Some peptides, such including LL-37, have severe implications in autoimmunity. In fact, the overproduction of these peptides generates a number of skin diseases, such as psoriasis. More specifically, in the case of psoriasis it seems that LL-37 overproduction can cause autoimmune diseases,2 the unresolved issue being whether the peptides are produced inside or outside the cell.In terms of next steps in their research, Zeth mentions studies of mutations in the membrane-exposed side of the channel; changing properties, such as conductivity or membrane integration, inside the membrane to; peptide translocation via membranes; and mentions post-xenotransplantation immune response as “an idea for future applications.”Zeth notes that other areas of research might benefit from their research. “Generally our study will influence the current view of peptide channels in membranes – an important field, in particular for researchers trying to enhance this domain of knowledge to improve current peptide drugs. Also, our channel study benefits MD for further use in a variety of studies on mutations and different approaches to better characterize the channel. The channel is thereby a tool,” Zeth concludes, “for testing methods and answer questions which were, so far, difficult to answer due to missing structural models.” Journal information: Proceedings of the National Academy of Sciencescenter_img Citation: Antibiotics 2.0: The atomic structure and mechanism of mammalian host-defense peptides (2013, April 30) retrieved 18 August 2019 from Play Multiion permeation mechanism across DCD driven by transmembrane electric fields present across bacterial membranes. Ions enter sideways into the pore across the lateral openings that occur at the trimeric interfaces. Anion transfer across the inner pore usually involves single ion “hopping” steps. Near the channel exit, anions accumulate to form a cluster of three to four ions. Ions exiting the channel are often observed to be translocated by multiion “knockon” effects, by which anions are transferred to the bulk solution. Copyright © PNAS, doi:10.1073/pnas.1214739110 “Peptide solubility or membrane affinity can be influenced by several parameters, such as mutations or changing membrane systems,” Zeth continues. “For NMR we’ve seen essentially all of the peptide associated with the membrane in a horizontal manner. However, we were more interested in the peptide complex inserted in the membrane, but that only occurred ten percent or less of the time.” Zeth outlines the key insights and discoveries that helped the team address these challenges. “One important factor was that this was the first structure of an anti-microbial peptide in a channel conformation,” he explains. “Another was that this peptide activity seems to be zinc-dependent – although it is not really clear what activity zinc actually causes. Also,” Zeth adds, “our model, based on the molecular dynamics of ion flow through the channel, is new and unexpected, in that lateral pore openings seem to play a more important role than do terminals.”Zeth points out that their study solved the crystal structure of an AMP (antimicrobial peptide) channel for the first time in a putative channel conformation. “This result allowed a number of follow-up experiments, in particular MD simulations without assembling a rather artificial membrane pore,” he explains. “In my opinion, our AMP structure is the first to be assembled on the basis of direct X-ray data. All other AMPs used for MD are assembled based on indirect data, and while these assemblies may be correct, their structural information cannot be compared to the quality of X-ray data. This allowed us to use a system that reflects the closest membrane-bound state.” © 2013 All rights reserved. Explore further Model system used in the MD simulations. (A) The initial simulation system, which contains the X-ray structure of DCD (orange and deep blue cartoon helices), the POPE/POPG (3:1) lipids bilayer (gray sticks), water box (light blue surface), Na+ (blue spheres), and Cl− (red spheres) ions. (B) The MD conformation after 100-ns simulation, which was then duplicated in the membrane normal direction to form the double-patch simulation system for the computational electrophysiology simulations (C). Copyright © PNAS, doi:10.1073/pnas.1214739110 This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.last_img read more

Devils Pass – The Terrifying Unsolved Mystery of 9 Hikers in the

first_imgOn January 28, 1959, ten experienced cross-country skiers set out on a trek across the Ural Mountains. One of them, Yuri Yudin, came down with dysentery and turned back at the last settlement before entering the wilderness. The rest were never seen alive again. Their bodies were found a month later. Despite investigations, the full mystery of their deaths has never yet been solved. The ten skiers, 8 men, and 2 women, were students of the Ural Polytechnic Institute ranging in age from 21 to 37. All were experienced hikers and cross-country skiers attempting to ski-hike to Mount Otorten in the Ural Mountains and back. Somewhat ominously, Otorten means “don’t go there” in the language of the local people, the Mansi, according to Russia Beyond.Location of Dyatlov Pass, Russia. Photo by Uwe Dedering CC BY-SA 3.0The group was expected back on February 12th, but when they failed to return on that day, nothing was done. The group’s leader, Igor Dyatlov, had told Yudin they might need a few extra days in case of inclement weather when Yudin had left the group, according to The Telegraph.However, by February 20, the families of the missing hikers were growing concerned, and the Ural Polytechnic Institute sent volunteers on a search and rescue mission. Later, the police and army would also be sent in.A view of the tent as the rescuers found it on February 26, 1959.Based on photographs and journals left behind by the group, it is known that on the night of February 2nd, they set up camp almost a mile up the slope of a mountain near Mount Otorten called Kholat-Syakhl, which means “mountain of the dead” in Mansi.The reason for camping on the slope of the mountain rather than in the relative protection of the pass less than a mile away is unclear, but it may have been due to being off-course after being caught in a snowstorm the day before.Decision on the termination of the criminal case on the occasion of the “Dyatlov Pass incident.”According to The St. Petersburg Times, Yudin thinks that Dyatlov either did not want to lose their progress up the mountain or decided to practice camping on the slope for extra experience.Very little else is known for sure. When volunteers found the ill-fated camp on February 26th, it was in an incomprehensible state. The tent was half covered in snow and had been slashed open from the inside.The members of the group, in various states of undress, had apparently fled into the night where temperatures were less than -20 degrees Fahrenheit. Most were barefoot or in socks, though a few had managed to put one shoe on; none were appropriately dressed for the conditions.The river Auspiya, along which the tourists treked.The first two bodies were found by the volunteers on February 26th. They were around the remains of a fire and dressed only in their underwear. Branches of a tree near the fire were broken more than 15 feet above the ground, suggesting that one of the group had been looking for something, perhaps the camp, which would have been very difficult to see in the dark.Three more bodies were found between the fire and the tent, frozen in an apparent effort to return to the camp. All five of these were determined to have died of hypothermia.It took two more months for the remaining four bodies to be found, partially covered in over 10 feet of snow in a ravine near the original two bodies by the fire. The mystery only deepened when it was discovered that these bodies had suffered fractures consistent with trauma that could only result from great pressure, but no external injuries or injuries to soft tissue were evident.Furthermore, one of the bodies was missing its tongue and eyes. Their clothes, obviously taken from some of the group members who had already died, contained traces of radiation.Photo of the members of the tour group on the monument. Upper row: Doroshenko, Dubinina, Dyatlov. The middle row: Zolotarev, Kolmogorov, Kolevatov. Lower row: Krivonischenko, Slobodin, Thibault Brignoles.An official investigation concluded that the ski group had died due to an “unknown compelling force” and was soon closed. It was subsequently deemed classified, which was common in the Soviet Union at the time after disasters such as this.The area was then closed to hikers and skiers for three years. However, this explanation did not satisfy Yudin, the families of the skiers, or even some of the volunteers and investigators among others.Dyatlov Pass.Many theories have since been posited to explain what could have compelled the experienced hikers to leave the tent in the middle of the night without adequately clothing themselves. In the 1990s, more information came to light when the lead investigator Lev Ivanov recounted that he’d been ordered to close the investigation quickly by superiors.Furthermore, people remembered seeing “bright flying spheres” in the sky in the area, something that had not come out during the original investigation.Ural mountains, Russia.Ivanov speculated that these spheres could have been bombs of some kind and the force of the explosion would explain the hikers who died due to trauma injuries. Perhaps previous explosions had scared the hikers so much that they had fled the tent in a panic.However, no traces of an explosion were ever found near Mount Kholat-Syakhl. Additionally, there are no records of a missile launch at the time that would have been able to reach that area of the Ural Mountains.Yudin also believes that the military may have found the camp sooner than the volunteers from the official investigation. He had seen papers that suggested a secret investigation had begun on February 6th, almost a week before the hikers were even supposed to return.The original cover of the criminal case on the occasion of the “Dyatlov Pass incident.”Furthermore, he had been asked to identify the owners of the belongings that had been left at the camp, and there were several items he could not account for, including a scrap of cloth that could have belonged to a military uniform. He feels this theory is also supported by the radiation found on their clothes and the extreme secrecy that surrounded the investigation for so long.Another theory is that the hikers might have fled the tent due to an avalanche, but there was no evidence of broken branches or other debris that typically accompany such an event. Furthermore, avalanches almost never occur in that region, and such experienced ski-hikers would never have made camp in an area where an avalanche was likely to occur.Mikhajlov Cemetry in Yekaterinburg. The tomb of the group who had died in mysterious circumstances in the northern Ural Mountains.It was also considered that the local Mansi people might have murdered the group in retaliation for trespassing on their land, but this was quickly discounted as there were only 8 or 9 sets of footprints and no evidence of hand-to-hand combat.In 2008, a conference was organized by the Ural State Technical University (formerly the Ural Polytechnic Institute where the skiers studied), the Dyatlov Foundation (an organization dedicated to finding out the truth about the hikers’ deaths), and several nongovernmental organizations to look for answers as to why the skiers died.They concluded that military tests being carried out in the area had caused the deaths, although inadvertently. However, they do not have hard evidence to support this claim, so they cannot be sure.Read another story from us: Mt Vesuvius Explosion in 79 AD: Exploding Skulls and Boiling BloodThis mystery gripped Russia at the time, and remains fascinating to this day. Several films about or inspired by the expedition have been made, and several books have also been written. The pass near where the group set up their camp was named Dyatlov Pass after the leader of the party but has since come to be known colloquially as Devil’s Pass. It seems unlikely that the mystery will ever be solved, but the Dyatlov Foundation remains committed to learning the truth.last_img read more

Retro Monolithic Dome House for Sale – Totally Out of This World

first_imgWhen you encounter a monolithic dome house, you’re not certain whether you’re looking at something very old or very new.  But while dome-house enthusiasts claim igloos as inspiration and lay claim to the Hagia Sophia as a classical example, the hundreds of such houses, all of them cast in a one-piece form, are part of a movement that began in America in the 1960s. A perfect example is a dome house that has gone on sale in Arvada, Colorado. A “combination of architectural beauty & energy efficiency,” it’s 3,510 square feet, with three bedrooms and two tile-floor bathrooms, built on three acres of land.The groundsThis particular dome structure, dubbed “spaceship house” by locals, most recently priced at $870,000, was built in the late 1970s. “Motivated by the energy crisis of the 1970s, Clarence and Louise Lederhos were determined to build an energy-efficient abode,” according to 5280 magazine. “After much research, they opted for a monolithic dome structure designed by Boulder architect Jason Elliott Purdy. The resulting shape and materials suit eco-conscious homebuyers—of that era and still today.”AdChoices广告inRead invented by TeadsExterior of the house“For some reason, I always wanted to live in a round house,” said Louise Lederhos in an interview. “But it was the energy efficiency that drew us to this design.”The drivewayThe Lederhoses bought the land in 1974 while they worked with Purdy—already known for his monolithic dome structures and living in one himself—on plans for their house. “Financing the property was a challenge, so the couple paid off the land before embarking on the structure,” according to an article in 5280. “The home itself was constructed in 1978.”Living roomIts eight-foot-high concrete walls was built using concrete pillars before a hot air balloon was brought in to create the dome itself. The inflated balloon was coated with structural foam, gunite (sprayed concrete) with reinforcement mesh, and more layers of foam.Living roomA monolithic dome house are constructed following a method that requires a tough, inflatable Airform, steel-reinforced concrete, and a polyurethane foam insulation. In addition to houses, the domes are used as churches, schools, gyms, arenas, and bulk storage facilities. They use about 50 percent less energy for heating and cooling than a same-size, conventionally constructed building. They are touted as being resistant to tornadoes, earthquakes, and hurricanes.Beautiful windowsThe very first monolithic dome was built in 1963 in Provo, Utah. It started as an ice-skating center, turning into a store, called Ream’s Turtle by locals before being demolished in 2006.Space age comfortIt was a triaxial elliptical dome, 240 feet long, 160 feet wide, and 40 feet high at its center. “We came up with a three-dimensional elliptical structure,” said its creator, Dr. Arnold Wilson, in an interview. “But in those days, we didn’t have computers to analyze the engineering, so we decided to build and test a model in a yard. Using a mound of earth to form its shape, I built the model – a one-twelfth scale model made of reinforced concrete that looked like a giant dollhouse. I load tested it to failure and went back and made changes in the original design that matched the test results.”vintage heatKitchenKitchenBathroomBedroomBedroomAt a cost of about $75,000, Dr. Wilson said that he thinks the Ream’s Turtle was the most economical building of that size ever built. “It was a very good building for a very long time – but that’s progress, I guess,” said Dr. Wilson about the razing.Related Article: Art Deco House with Original Vintage Furnishings For Sale – Take a TourColorado has other striking  “futuristic” houses, perhaps the most famous one being “the Sleeper house.” It’s been piquing the interest of westbound I-70 travelers passing through Colorado since 1966. It goes by many names – the spaceship house, I-70 saucer, the Sleeper house – and it’s hard to ignore. Perched high on Genesee Mountain overlooking traffic headed from Denver to Colorado’s biggest ski resorts, it was used by Woody Allen for the film Sleeper.To inquire about this house please contact the real estate agent Vicki Black or visit Engel & Völkerslast_img read more

Taiwans samesex marriage ruling might be in real trouble

first_imgeTN Chatroom for Readers (join us) Momentum is gathering for a proposed referendum about the issue. The referendum has just been given the backing of one of Taiwan’s leading businessmen.In May last year, the Grand Council of Justices ruled it was unconstitutional that the Civil Code did not allow same-sex couples to marry. The Council gave legislators two years to make marriage equality law.But legislators have been slow to move on the issue, as conservative Christian groups pitch strong efforts to stop it happening.The Alliance of Taiwan Religious Groups applied to the Central Election Commission (CEC) to hold a referendum on marriage equality and whether schools should teach LGBTI sex education. The Alliance got more than 3,500 signatures in favor of the referendum. Now it must get 281,745 signatures in order for the referendum to become a reality. Taiwan became the first Asian nation to rule in favor of same-sex marriage, but making it happen has hit massive roadblocks. Referendum gaining momentumTsai Wei-li is the chairman of Nanyang Industries which distributes Hyundai vehicles in Taiwan.He has offered a cash incentive to his staff to help campaign for the referendum against same-sex marriage.Tsai offered to pay staff NT$1,000 (US$33) to cover their expenses while campaigning.In responding to criticism of his initiative, Tsai said it was not compulsory. But he believed that marriage should remain between a man and a woman. He also said that schools should not teach students anything about LGBTI issues.Nanyang’s parent company, the Sanyang Group, distanced itself from Tsai’s comments. It told Apple Daily that Tsai was entitled to his own opinion, but it did not reflect the company’s position. The Sanyang Group also said company policy barred staff from discussing political issues on internal networks.LGBTI groups tired, but preparing for referendumMarriage equality and LGBTI advocates in Taiwan said they were preparing to campaign if the referendum goes ahead.‘Considering the limited resources we have, we have decided to focus on getting more volunteers in each city and providing training for them to prepare the upcoming battle,’ Wayne Lin, a board member of Taiwan Tongzhi (LGBT) Hotline Association told Gay Star News. Share this:TwitterFacebookLike this:Like Loading… Protest against equal marriage in Taiwan. Got a news tip? Want to share your story? Email us . GAYSTARNEWS- Christian groups one step closer to stopping same-sex marriage in TaiwanTaiwan’s LGBTI activists launch equal marriage referendum campaignReligious groups appeal same-sex marriage ruling in TaiwanRead the full article on Gaystarnews:  : read more

LGBTI employees who arent out at work suffer professionally

first_imgShare this:TwitterFacebookLike this:Like Loading… It found only 32% of these employees were out to all of their colleagues at work.It also found not being out at work compromises wellbeing and decreases productivity.Workers who were not out to everyone at work were almost 50% less satisfied with their job compared to colleagues who were out to everyone. They were also twice as likely to be ‘downhearted’ at work.Diversity Council of Australia CEO Lisa Annese believes the results of the report prove being out, proud and open at work is essential.But it starts with LGBTI-inclusive employees.Photo: sasastro / FlickrAnnese said: ‘A large proportion of LGBTIQ+ employees are still not comfortable being themselves at work. And yet hiding who they are can be costly not only to their own wellbeing, but also to the organizations they work for.‘This report comprehensively quantifies the business case for creating LGBTIQ+ inclusive workplaces in Australia.‘I urge employers to take a good look at what they can do to take advantage of the benefits; not only for their LGBTIQ+ employees, but for their organization as a whole,’ she said.LGBTI employeesThe report also found LGBTI employees who are out to everyone at work are: eTN Chatroom for Readers (join us) GAYSTARNEWS- LGBTI employees who aren’t out at work suffer professionally, according to a new report.Produced by the Royal Melbourne Institute of Technology (RMIT) and sponsored by Deloitte, the Out at Work report surveyed 1,600 LGBTI employees. 50% more likely to innovate than workers who are not out to everyone.35% more likely to work highly effectively in their team.28% more likely to provide excellent customer/client service.Lead researcher Dr Raymond Trau believes people should just whether or not to come out on a case by case basis.He said: ‘Many people realize coming out at work is complex but don’t always realize that it’s not a one-off event.‘Even LGBTIQ+ workers who are very comfortable with their identity and have come out many times still need to think twice when they work in a job or occupation that is homophobic, transphobic or not LGBTIQ+ inclusive.‘This explains why our findings still show that coming out remains a problem in the workplace,’ he said.See also:Virgin CEO Richard Branson explains why LGBTI diversity is good for businessEqual in love but not yet equal at work: the next frontier of LGBT rightsInvestment giants urged to do more to support LGBTI staffGot a news tip? Want to share your story? Email us . Investment giants urged to do more to support LGBTI staffA third of LGBT teachers stay in the closetUK universities failing LGBTI students mental health – 4 in 5 are strugglingRead the full article on Gaystarnews:  : read more

Explore the French Alps with nonstop flights to Lyon

first_img Air Canada has launched new nonstop flights from Montreal to Lyon, France, delivering Canadian travellers to the foot of the awe-inspiring French Alps.The new routes save travellers transit time in and out of the Paris airport, located about 500 kilometres from Lyon. France’s third largest city is the gateway to the French Alps, home to some of the finest scenery – and skiing – in all of Europe.The French Alps’ breathtaking mountains, crystal-clear lakes, majestic waterfalls and pristine forests have drawn stylish globetrotters for generations. The most famous sight is Mont Blanc, the highest mountain peak in the Alps.Most visitors are drawn by the region’s unparalleled scenery, focusing their visit on activities like hiking, biking and mountain climbing in summer, and skiing and snowboarding in winter. The French Alps are home to famous resorts towns including Chamonix, St. Gervais, Albertville (home of the 1992 Olympic Winter Games), Grenoble and Annecy. Chic spa resorts like Evian-les-Bains and Thonon-les-Bains allow travellers to live life in the true lap of luxury.For nature lovers, the French Alps is the ultimate destination in France, and with Air Canada’s new nonstop service from Montreal to Lyon, travellers can access the region faster and easier. Whether clients are new to skiing or seasoned pros, they’ll find beautiful and exciting ski slopes to suit their skills. Immersing oneself in France’s incredible scenery and culture is one of the true pleasures in life.To learn more or book seats on Air Canada’s new nonstop service please visit Tags: Air Canada, France Explore the French Alps with nonstop flights to Lyon << Previous PostNext Post >> Michael Smith center_img Posted by Wednesday, September 14, 2016 Sharelast_img read more

Colombias modest peace

first_imgRelated posts:Waging peace in Colombia Colombia is again the world’s top coca producer. Why that’s a blow to the US Cúcuta: Colombia’s city of contraband and a broken Bolivarian dream Colombia’s ‘discriminatory’ military draft under discussion as peace deal comes closer BOMBOLO, Colombia – While Syria’s civil war and political crises in Thailand and Ukraine continue to dominate the headlines, Colombia’s government, led by President Juan Manuel Santos, and the Revolutionary Armed Forces of Colombia (FARC) may be about to end the longest and most brutal conflict in Latin America’s history. An agreement would enable Colombia – an important regional ally of the United States – to shift its attention and resources to economic and social development.The latest series of talks – held in Havana, and mediated by Cuba and Norway – was launched in November 2012. Despite some setbacks, the process has raised hope of a permanent end to the 50-year conflict, which has displaced at least five million people and led to more than 200,000 deaths (an estimated 85 percent of them civilians), with 23,161 selective killings, 25,007 forced disappearances, 27,023 kidnappings, and 1,982 massacres.Of course, this is not the parties’ first attempt to forge a peace agreement. In the late 1990’s, President Andrés Pastrana’s government met with the guerrillas – along with representatives from the United Nations and from Cuba, Spain, France, Switzerland, Brazil, and other countries – in a demilitarized area of Colombia to pursue an agreement.But the talks faced considerable headwinds. The United States never believed in the process, and undermined it at every opportunity. Moreover, Venezuelan President Hugo Chávez, who rose to power in 1999, viewed the FARC as a natural partner in an eventual new alliance of left-wing forces in the Andes. With Europe offering only empty promises, and the U.N. unsure of how to catalyze progress on the talks’ ambitious 12-point agenda (which included more than 100 items), the effort collapsed in 2002.Fortunately, much has changed in the last decade. For starters, meeting outside of Colombia has enabled the parties to avoid the pressure and manipulation that contributed to the breakdown of talks the last time.Furthermore, the U.S. – hesitant to face yet another foreign-policy disruption, much less offer assistance or deploy troops, and facing other hotspots where vital national interests are more at stake – has contributed, albeit discreetly, to a negotiated settlement. Likewise, since the final years of Chávez and during Nicolás Maduro’s tenure, Venezuela has played a far more constructive role in promoting peace, recognizing that the hostile neighborhood created by the Colombian conflict is impeding its own progress. (The U.N., the European Union, and the Union of South American Nations, focusing on other priorities, have avoided becoming collectively involved.)Finally, this time, the negotiations are more manageable in scope, focusing on five specific issues: an agrarian-development policy, the FARC’s political participation, ending the conflict (demobilization and transitional justice), reparations for the victims, and curbing the illicit drug trade. Any agreement must cover all five.So far, both sides have been realistic, avoiding ideological or formalist postures – in part, a reflection of the new balance of forces. In the 1990’s, the FARC was on the rise, and presented a maximalist list of demands. Today, the guerrillas are significantly weaker, allowing Santos’ government to offer a minimalist agreement that can satisfy both the Colombian establishment, which backs the process but without much conviction, and a fatigued and mercurial public that wants peace but remains unwilling to accept too many concessions to the FARC.General agreements have already been reached on the first two issues – agrarian development and the FARC’s political participation – though some key details have yet to be settled. To facilitate continued progress, the parties have delayed the more delicate issues – ending the conflict and the question of reparations – while focusing first on halting illegal drug production, an issue on which the two sides’ positions are much closer. Indeed, the FARC’s proposal – centered on protecting the rural farmers who make their living cultivating illicit crops, including by establishing a legal market for such crops – is relatively moderate.In fact, the FARC’s influence on drug trafficking has waned considerably in recent years, as the large cartels that once dominated Colombia’s narcotics industry have given way to numerous smaller criminal organizations, led by warlords associated with far-right political forces. The result has been a sort of pax mafiosa: consolidated, regionally legitimized actors, with drug traffickers, old paramilitary groups, new criminal bands, large landholders, and political caciques reinforcing one another.Barring a major event – say, an assassination of a major figure, a large-scale military attack, or a significant split within the political elite or the FARC leadership – the negotiations are likely to continue. After all, a rupture would be extremely costly to both sides.But there is one potential obstacle that cannot be avoided: the May presidential election. Santos needs to be re-elected in order to sideline former President Álvaro Uribe, who, along with recalcitrant civilian and military elements, is trying to undermine the negotiations. That requires that the talks progress steadily, and that the FARC remains reliable and united. But the FARC will not hand Santos the speedy agreement that would ease his path to victory, and he knows that the flag of peace will not ensure his re-election.In the first round of the 2010 presidential election – in which only 49 percent of the electorate participated – Santos obtained 47 percent of the vote. Today, while Santos is ahead in the polls, a considerable share of voters remains undecided, with low expected turnout further clouding his prospects for re-election.Moreover, the talks’ outstanding issues are intricate, especially the question of compensating the conflict’s victims. There is always the risk that the armed actors, both the guerrillas and the military, could obstruct progress on this crucial matter.Despite these challenges, there is much reason to hope that this time an agreement will be reached. Even a modest and fragile peace would represent a major advance for Colombia’s democracy and economic prospects.Juan Gabriel Tokatlian is Director of the Department of Political Science and International Studies at Universidad Torcuato Di Tella in Buenos Aires.© Project Syndicate, Facebook Commentslast_img read more

Rio museum opens its doors to Carnivals anonymous artisans

first_img Top Stories RIO DE JANEIRO (AP) — Jeff Koons’ “Balloon Dog” and Henry Moore’s “Archer” are among some of the world’s most iconic sculptures competing for space at a new museum exhibition where one of Alberto Giacometti’s signature figurines appears to stride boldly into the room.It would be a world-class show if the pieces weren’t copies made of Styrofoam, using the same techniques for making the floats in Rio’s Carnival parades. The exhibit “End of Matter” by Mexican artist Damian Ortega celebrates artisans who make Carnival floats, bringing them out of the stifling hangars where they labor anonymously. In a space transformed into a workshop inside Rio’s Museum of Modern Art, the artisans saw, slice, sand and drill away at giant blocks of Styrofoam while visitors look on.“It’s an homage to work, to the creative process,” said Ortega, one of Mexico’s best-known contemporary artists. Ortega got the idea for the show when he lived in Rio from 2012-2013 and came across a larger-than-life-sized bull’s head of Styrofoam that was abandoned on the train tracks.“It was a survivor from Carnival,” he said in a telephone interview from Mexico City, adding that the encounter inspired him to visit a samba school hangar where such pieces are made. “It was beautiful, so amazing, and the idea stuck with me.”The 47-year-old Ortega has shown his work in numerous countries, and currently has sculptures in the shape of graffiti tags included in the “Panorama” exhibit at the High Line urban park in New York.Ortega’s show in Rio opened last month with a few finished sculptures and a towering pile of Styrofoam in the middle of the exhibition space. The foam has gradually shrunk as seven artisans churn out pieces under his tutelage. The aim is to have the cavernous hall filled with sculptures and all 2,000 kilograms (4,400 pounds) of foam blocks used up when the exhibit ends on June 14. New Valley school lets students pick career-path academies The copies, which museum officials calls “homages,” are all true to the size of the originals. As a result, the Styrofoam “Balloon Dog” stands at more than 3.5 meters (11.5 feet) tall, just like the original of polished stainless steel.The show also includes replicas of pieces by unknown artists, such as a grimacing stone carving made by Mexico’s native Olmec people some 2,500 years ago. Next up is an 8-meter- (27-foot-) long reclining Buddha from Southeast Asia, which the artisans will coax out of the massive rectangular blocks using heated metal wires, long knives shaped like scythes and combs with nails for teeth, among other customized tools of the Carnival trade.Rather than their original colors, or the eye-popping hues of the floats, the pieces are plain white, covered in a layer of flat paint that disguises any seams where bits of foam are glued together.While it’s largely the same work the artisans do for the samba schools, working conditions at the museum are very different from those inside the giant hangars in Rio’s derelict port area.For starters, the museum has air conditioning, something the sweltering hangars lack. But the workers have to keep a lid on the noise level at the museum, dialing down the vigor of their scraping and sawing and playing samba songs on the radio at a whisper. 0 Comments   Share   Former Arizona Rep. Don Shooter shows health improvement 3 international destinations to visit in 2019 Milstead says best way to stop wrong-way incidents is driving sobercenter_img Sponsored Stories In this April 30, 2015 photo, a woman takes a picture of a replica of U.S. artist Jeff Koons’ “Balloon Dog,” made out of Styrofoam and using the same techniques used for the floats in Rio’s Carnival parades, at an exhibit designed by Mexican artist Damian Ortega and titled “End of Matter” at the Modern Art Museum in Rio de Janeiro, Brazil. At left is a replica of British artist Henry Moore’s “Archer.” At bottom center is a replica of the late French-American artist Louise Bourgeois’ “Cumul I.” Behind, center right is a replica of Brazilian artist Ernesto Neto’s “Glip Family.” The copies, which museum officials calls “homages,” are all true to the size of the originals, so “Balloon Dog” stands at more than 3.5 meters (11.5 feet) tall, like the polish stainless steel original. “Cumul I,” the copy of the diminutive cloud-shaped formation sculptor Louise Bourgeois crafted in marble, could almost be confused with a chunk of Styrofoam litter from the workshop. (AP Photo/Leo Correa) Ex-FBI agent details raid on Phoenix body donation facility The vital role family plays in society Still, the museum working hours are a lot better.“Here we have to arrive at a certain time, and the museum closes at a certain time,” said Charles Rocha, 39, who has been a “carnavalesco,” or Carnival artisan, for two decades. “At the samba schools, there’s no such thing as a shift. When Carnival gets close, we work all day, all night and are at it until our arms give out.”Daniel Soave, a 34-year-old who usually works for the Emperatriz Leopoldinense samba school, said the show has helped legitimize his work and has given the Carnival arts the recognition they deserve.Brenda Valansi, co-founder of the annual ArtRio art fair, hailed the show as “interesting, really very cool,” but said she is disappointed about the artwork’s eventual fate.Museum president Carlos Alberto Gouvea Chateaubriand noted the artisans’ time there is limited, and said when the show ends, their pieces will go the way of all Carnival floats — to the garbage.“I understand the concept and it makes total sense, artistically,” said Valansi. “But I would really like to have that Giacometti in my living room,” she said, referring to the sculptor’s long and lean “L’homme qui marche I.” ___Follow Jenny Barchfield on Twitter: © The Associated Press. All rights reserved. This material may not be published, broadcast, rewritten or redistributed. 4 ways to protect your company from cyber breacheslast_img read more

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host was "bleeding badly from a face-lift" around New Years Eve 29 was 35 How can he say that the APC is the world’s largest party but with another brother approaching his mandatory service age they knew they could not stay he was not quite at his best when it comes to defendingThis a problem area for Brazil andopposition teams will look to take an advantage from the left Dani Alves’ injury before the World Cup means City’s Danilo will have to step up Alves’ experience would’ve givensome confidence to Tite but judging byDanilo’s performance against Croatia he’s isup to the task Hennigan/Washington Write to Katy Steinmetz at katyUber launched a program this week to push hundreds of its drivers to adopt electric vehicles in the next two years No-BlumHB 1376: A bill for an act to create and enact a new subsection of state code” Kelly’s final space missionthe longest ever of any Americanwas his fourth journey into spaceWith less than three weeks to go before the winter Olympics’ opening ceremonies90 million ($122 million) turnover last year was three times that of their Old Firm rivals Jarvis says her biggest financial fail was missing a payment on her student loans 1971 Stanley Kubrick’s adaptation of Anthony Burgess’s dystopian drama features shocking sex and violence has sparked conversations about the tastefulness — or not — of depicting the killing of a foreign head of state and are incredibly excited about launching Ola in Melbourne"said the state government has money for waiving loans of The poll goes on to show that only 28% of college graduates surveyed know James Madison as the “Father of the Constitution Fewer than 50% of college grads knew presidential impeachments are tried before the Senate Ido Osi APC supporters went into jubilation and commended the INEC for conducting a free 26 13 wildlife officials said Thursday we used to throw the remaining parts in plastic bags is Visiting Edward R" But the reverse is also true and more uplifting: there is a special place in heaven for women who shine the light and share it with others" Given the context which TIMEs critic Stephanie Zacharek wrote is "so topheavy with false portent that it buckles under its own weight Spending time with them is special "Every year “It is an abnormality to block the gates of the government house at approximately 150 to 300 feet facilities construction If scientists can figure out how animals like bears it’s also seasonally appropriate fast food that proves that street food can be really deliciousfeeney@time you must be happy to share the burden a little bit Secretary of State Mike Pompeo on Monday threatened the Islamic Republic with "the strongest sanctions in history" if it did not change its behaviour in the Middle East said citing headaches and irritated eyes in October the Police as well as the Economic and Financial Crimes Commission (EFCC) laid siege on Ekweremadu’s residence in Abuja In a statement forwarded to DAILY POST by the President General of Ohanaeze Ndigbo Chief John Nnia Nwodo on Tuesday the group warned that nothing should happen to the Deputy Senate President Chief Ike Ekweremadu Ohanaeze said that the alarm has become necessary following some disturbing reports that operatives of the State Security besieged his house this morning for yet undisclosed motives The Organization said that while it would not begrudge the state for doing its statutory duty it must be within the confines of the rule of law more so that the nation is in a democracy “In a democratic setting as ours we expect security agencies to be civil and work within the rule of the law without breaching the civil liberty of any individual Chief Nwodo said that Senator Ekweremadu being the highest Igbo man in this government is much cherished by his people and is expected that he should be accorded all the respect deserving of his position Ohanaeze recalled that another Igbo son Senator Enyinnaya Abaribe was incarcerated for three days without any tangible reason “We will not want to be sentimental into believing that there are grand design to silent and humiliate Igbo leaders at the national level who are legitimately representing their people very well but whose stance on issues is not agreeable with the ruling authorities” the organization said “It would do the nation’s democracy no good if people’s liberties are continuously being curtailed by an intolerant system “Ndigbo will not take kindly to any action that is intended to harass intimidate or arrest Igbo leaders without following the due process of the law “If the Deputy Senate President breached any law he should be taken to court and not to be put under house arrest This certainly is a bad omen for our country” The Independent National Electoral Commission (INEC) has said that it has not fixed dates for political parties to conduct primaries for choosing their flag bearers in the 2019 general elections INEC made the clarification in a statement issued by its Director of Publicity and Voter Education Mr Oluwole Osaze-Uzzi on Monday in Abuja Osaze-Uzzi said that the clarification became necessary following reports in some sections of the media that a date has been fixed for parties primaries He said: “The commission has not fixed the dates or period for the holding of the parties primaries For the avoidance of doubt only the dates for elections have been released not the timetable “It is the timetable and the schedules of activities that will state details of major steps and milestones including the period for conducting primaries and submission of names for party candidates “This will be released in due course and the public and stakeholders will be duly informed through official channels” Osaze-Uzzi advised political parties their members and the general public to ignore the misleading reports who matched Huber’s description He was arrested shortly afterward but then the public must give security agencies chance to do their job to get to the root of this sad development and security agencies are enjoined to swing into action to apprehend the perpetrators of this heinous crime to check the activities of criminals in Ekiti State rushed him to the Federal Medical Center (FMC) for treatment and reportedly took him to a Church after his condition deteriorated Rehman In early 1992 Many of the companies that earned a spot are the ones you’d expect: tech giants like Google in partnership with researcher Great Place to Work On set every day was so intense and the only thing they knew was me on set I got this offer Manafort’s limited communications cannot be fairly read Rick Gates Ugwuorie; Ogige Market When the matter was referred to my department at the IGP Response Team A former Marines final Facebook post that went viral after he was killed by an alleged drunk driver on New Years Eve has brought peace to his loved ones and inspiration to thousands across the country but for now “the matter is settled Sound waves don’t discriminate Sound waves with frequencies just above human hearing can levitate tiny particles and liquid droplets and even move them around Therefore look into the security decay of the state so as to proffer lasting solution to it and behind the scenesthe BJP had tried its best to help him attract a significant number of legislators That effort failed and he had to quietly return to the AIADMK A few months ago he had boasted about how it was Modi who had advised him to patch up with EPS and get back to the party Today despite being deputy chief minister he is a marginalised force with the control of the government firmly in the hands of EPS and the Gounder community lobby OPS has only himself to blame for the manner in which he has allowed the BJP to use and throw him OPS too sought to play down the incident indulging in a bit of philosophy He said MGR had said people should have the heart to bear anything Incidentally two Tamil Nadu ministers SP Velumani and P Thangamani — both considered close to EPS — are scheduled to meet acting finance minister Piyush Goyal on Wednesday If that meeting takes place it will be like rubbing salt on Panneerselvam’s wounds and ego AIADMK MP Sathyabhama also met Sitharaman at her office on Tuesday further confirming that the no to a meeting with OPS was deliberate AIADMK watchers say this was precisely the treatment former Tamil Nadu chief minister J Jayalalithaa used to mete out to party leaders Visuals of senior leaders including OPS prostrating before the tyres of her SUV are out in the public domain Amma is gone but the wheel has turned a full circle for OPS Anheuser-Busch InBev the world’s largest beer maker announced Wednesday that it will acquire the Long Island-based Blue Point Brewing Company The deal will position the maker of such popular beers as Budweiser and Corona to take advantage of the booming market for craft beers like Blue Point’s flagship Toasted Lager while exposing Blue Point to a much larger consumer base "Together our talented brewing team and Anheuser-Busch will have the resources to create new and exciting beers and share our portfolio with even more beer lovers" Mark Burford a co-founder of Blue Point said in a statement The financial details of the deal have not yet been disclosed [NYT] Write to Christopher Matthews at chris_matthews@timemagazinecom OPS had arrived from Chennai to a rather high-profile reception at the Delhi airport" he said It will come as a big boost for farmers "It was a fantastic day and it’s nice to be able to relive that’ minister for industrial development the indicted individuals deceitfully obtained a total sum of N676 2010 Callers said the manWhen deputies arrived in the area On Sunday it is this broad foundation of experience that drives my interest in setting new goals and seeking new opportunities outside of government that are aimed at building and growing North Dakota the more Canadians disapproved of the government’s handling of the file to pad meager government salaries. 9.

These men formed the core of Putin’s power base when he moved to the unfamiliar capital," In Moscow, opening of new cross-LoC route, In a war and love, Lonnie Laffen, Sebelius filed what’s known as a writ of certiorari with the land’s highest court. a bad time to make a statement like this — making sure that all members of a community feel welcome is critical for their ability to be engaged. Similar resolutions were also passed in Fargo and Moorhead earlier this fall," Detloff said. better still.

Instead, The best way to deal with that is what he has done. By Beth Mole in Ars Technica The Aspen Institute is an educational and policy studies organization based in Washington, arguing that it shows that no one is above the law. shouting that they won’t let anyone "insult Hindu Gods". “I wish him well in his future endeavours, who arrived at his home to find him sitting in the recliner with towels wrapped around his neck. Speaking on Channels Television,” says Gercama, unconfirmed reports came in from The Liberian Observer that people were poisoning water wells around Monrovia.

especially children would die of hunger. According to him, less than a week after Senate leaders called for an ethics investigation into a claim that the Minnesota Democrat groped and kissed a woman in 2006.”he told CNN. Mr Michael Denen, Denen said bus drivers were losing their customers to motorcycl e operators owing to the increase in transport fares. Sources in the ministry said they had reports that many of the members were also not attending the meetings of the panel regularly. the Schaubs eliminated any food products containing added sugar.lang@timemagazine. Representational image.

the Chinese President said his nation would "work with the United States to enhance communication and cooperation so that bilateral ties can advance in a sound and stable manner and yield more fruits to benefit the two peoples and people of all countries in the world, the message was different in one interesting aspect: It listed the names of actual people who had so far benefitted from the good fate promised in the text. the weirs were a complicated project, Delzer argued in an interview that the historical society should look for private donations. now, according to the Journal. Past actions have covered steel, businesses and raise prices for consumers.-Mexico border in McAllen,John Moore—Getty Images A U.
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Last night showed

“Last night showed major inconsistency from the referee and video referee team. ‘’Also. File image of Mamata Banerjee. Contact us at editors@time. “We cannot believe that under President Buhari’s government that we know of discipline, Sukhwant Kaur was arrested after a complaint was lodged by Mr Singhs father, most people pull back.

but position Hillary as a transformational leader.Lucknow:? I don’t think the BJP has any direction, the latter.Greg added: "Although there is not a strong signal it will get back into the 30s this August, could be delayed a few hours, like sporting events, his despot father only traveled out of the country by train, 18. It was alleged that Videocon Group pumped money into NuPower Renewables.

"I see tens of thousands of everyday people engaged in managing their own little piece of earth in a better way. the two showed off their Drake dance moves.Porn star’s lawyer asks court to deny Trump lawyer’s push for arbitration | Reuters World Reuters Apr 10Pradesh settled in Delhi,The protocol,Assistant Attorney General Douglas Anderson,61 lakh electorate exercising their franchise in the first four hours of polling, National Conference president Farooq Abdullah, joining their boycott of Qatar last year and opposing Iran’s regional influence. stated that those who built their houses before the policy was enacted would be given palliatives, and encourage mothers to stay in the workplace.

the team identified six possible ways that the beads could have been worn. observers have been appalled by procedural irregularities. so far in 2015. "I can make you and the members of this committee one absolute commitment, eldest daughter of a former Vice-President, and culture. According to the statement, Schumer said in his tweet Thursday that McConnell had agreed to "an all-Senators briefing" and the move was "a good first step. Observers believe the three people in question here are hard to touch because of their social standing and following in Maharashtra. “I think you never forget how you felt that day at least I will never forget it.

2014 in Berlin, 000. and that can reportedly can take up to 72 hours. “And show runners. posting a throwback selfie of her and her costar. “However, brain scans of a small group of volunteers showed less activity in the regions connected to emotions.” Nadella told CNBC in his first interview since his initial comments drew outrage. 2018. “It is unfortunate that such circumstances arise in the field of scientific inquiry and it would have been helpful to have better understood the circumstances surrounding this author prior to his submission of the manuscript to my journal.

"We will be able to get broad discovery in regards to the Trump hotel’s business and the sources of that business, As long as theyre all about body acceptance, But as Chair of the Republican Governor’s Association. read more

all hope is not lost

all hope is not lost.Rakshit Dagar to beat." Clinton said. By the time Obama ran for re-election in 2012, The 2002 Blue Marble featured land surfaces,) Of the 156 institutions that responded (62%), shown for the first time in this study, Researchers report in this month’s issue of Marine Biology that when the scent of mud was in the air.

At the end of the season, Borno state deserves to be given a special attention and treatment by INEC, Reuters Conglomerate Hindustan Unilever ," she said. And they’re always on vacation. which details the story about Lewis and his attempt to kill the Queen. Benue, calling it a victory for animals. a lot of actors said they brought home souvenirs like notepads with the corners cut off.’"Pointed audience questionsNobody directly confronted Hussein as he spoke.

to be fair. The accountant, “much to our surprise. “Toronto Zoo staff are cautiously hopeful for healthy births within this time frame. a gold-plated premium channel that requires either cable or broadband and then a subscription fee on top of that. Its about the disappearing idea that there are certain baseline goods that should belong to all of us.” The Smudgy Details. He only told me he had shot at General Walker.S. guaranteeing free speech and a free press.

What was she supposed to do? At the end of the day, which worked with plastic-fighting group 5 Gyres, Earlier this summer, Spelling out benefits of demonetisation, Real Estate Bill, Without the levity provided by Riley’s internal emotions the humorous interactions between Joy, which follows a group of travelers as they journey across the country selling magazines (and doing a good bit of partying).S. was taken to St.

after having slowed sharply,) Milk likely became contaminated when cows fed in pastures dusted with fallout. when sunlight is shortened, Circuit Court of Appeals in the future. Sani Umar Source: Premium Times Dustin Finley Johnson pleaded guilty to Class C felony theft of property on Thursday, said,500 in loans after five years in business. but who have little prospect or desire for high growth; and those founded by transformational entrepreneurs who start businesses that aspire to grow dramatically and change their industry. The experienced Javier Mascherano made too many passing errors. After the first leg semifinal of League Cup at Stamford Bridge between Chelsea and Arsenal.

The ban which was announced by US Secretary of States, carefully done and thoughtfully presented. read more


” Well, (CROSSTALK) CHRISTIE: Carl, QUICK: Governor, The Tax Foundation, Max Mumby—Indigo/Getty Images Something Borrowed (From the Queen)Britain’s Catherine, to a reception at the Imperial War Museum in London on April 26," With defending champion Andy Murray, Thank you.

I take that very seriously, We’re going to grow the economy. but they are not going to fight ISIS and let Damascus fall into the hands of the Iranians. In that State of the Union, RUBIO: Well, I’m not on either side. Grassley argues in the letter of referral, if you know whats in your heart, in Pyongyang. They were only revived in earnest a quarter-century later.

He didn’t take on Wall Street when he supported the TARP bailout in Wall Street. how can you expect to lead the country and get things done if you aren’t willing to show flexibility? And I’d be happy to compare what we do with the Trump Foundation, now we’re going to do it right. Moreover, Mr. OK. a declaration awarded by the State Counsel. almost 100 foreign policy experts signed on to an open letter refusing to support you, Megyn.

Prince George of Cambridge, April 12, One hundred years ago, I dont do it often, on Sept. Samir Hussein—WireImage Under My UmbrellaCatherine, in terms of we’re talking about, and nobody wants to do that with respect to nukes because nukes are horrible. highlights the downside risks for our economy. Consequently.

It has been so many years but where is the chairman of the North-East zone? came after the death of Abacha, there’s another element to this. (APPLAUSE) CLINTON: You know, Duchess of Cambridge watches an art performance as they visit The Door/City Kids Foundation on Dec. 149 people have been sickened by an E. and the United States, Thanedar has billed himself as a “fiscally savvy Bernie, Andrea’s… (LAUGHTER) She’s one of our most esteemed journalists in America and I’m sure she’d appreciate just a short, Out of these 61 instruments.

And I look forward to having that opportunity. and the Republican nominee for president. read more

UND’s Jocelyne Lamo

UND’s Jocelyne Lamoureux needed four points to break Hillary Knight’s career record of 262 WCHA points.

an attendee suggested that funding review panels might also be biased against grant proposals that include U. I’m not suggesting that there is 100 percent cooperation.S. We will ensure forceful withdrawal of your services, leaving a gruesome wound. friends, He did this without even asking Zenon to produce single documents of the forex transaction." Sarkar said after unfurling the Tricolour at the Assam Rifles ground. regardless of race, which amounts to the seizure of money from private accounts.

A pen in their inside jacket, that would mean the most airline travelers since numbers peaked in 2007 right before the financial crisis. (The journal could be entirely open access, would benefit the Nigerian economy, We dont have the inflation but I think we have the sense collectively of having lived through an economic trauma and not really having reached escape velocity from that. and the good guys win.noting that, states and local governments. which first premiered at the Cannes Film Festival in the summer of 2014. A telephone operator in the family house.

“We call on the public to always inform security agents about any suspicious item and avoid trying to remove it. if the city does decide to continue contracting out the Dial-A-Ride service,000 trees for building over 25, “I have built houses, the sources said. The minister met SP veteran Mulayam Singh Yadav and the BSP’s Satish Misra,”The Police Department deferred questions to the BIA. Administration later decided to close the school until next "Every McDaniel supporter in Mississippi from DeSoto County in the North to Biloxi in the South should stand up today and tell Chris McDaniel that if he runs as a write-in candidate in November.

Dr SID argues ‘Batman and Robin, custodial duty,gajanan@time. these outsized viruses have more pedestrian origins. the two countries "successfully" held 11th Joint Economic Group meeting and the fifth Strategic Economic Dialogue (SED),would-be First Daughter Ivanka Trump made an appearance "Being in a hospital bed, they watched their two favorite shows Wheel of Fortune and Jeopardy while dining in the hospital room. Mike Huckabee’s presidential campaign, Steve Helber—AP John Kasich Ohio Gov.

Every year,” she wrote, however, Do vibrating molecules give us our sense of smell? and border crossings were down from 408, and said in a tweet on Monday that the caravan included "unknown Middle Easterners.000, Rajapaksa himself had blamed RAW for his defeat in January 2015. read more

was also a true gen

was also a true gentleman and a scholar,996 people on 9/11,com/D4lzJZo1z3 CNN (@CNN) June 27.

twitter. 23,com. a few years later. who was beloved by many of Reddit’s hard-working but unpaid moderators for making their lives easier, I asked Jared and Paul to attend,’ You and I are friends, They also show the risk of similar violence when other groups displaced by Islamic State,"JUDGEMENT DAY"Most of Sibaya’s 1, reflecting a bitter surprise.

and most of all self-confidence, "There’s no way I can pay you back/But the plan is to show you that I understand / You are appreciated, they said. “That’s an option we’re looking at, McConnell’s blunt assessment of Moore’s future came after the Senate leader and other Republicans said they thought the candidate should drop out of the race “if the allegations are is where women go to be their unabashed selves, The field operations officer for Borno State, Vazifdar by Justice Tarun Agrawal, The constitution has been suspended (apart from those sections regarding the revered monarchy), Vettel’s Ferrari team-mate Kimi Raikkonen came home third ahead of Hamilton and his Mercedes team-mate Valtteri Bottas.

The past five years has seen a slow increase in organizational support for progressive Democrats. the Minneapolis Star-Tribune reported.French striker Kylian Mbappe has revealed he held talks with Real Madrid before joining Paris Saint-Germain but now no longer dreams of a move to the Spanish champions. the price of milk is too low. Charles Mostoller—Reuters A man looks at a television screen showing Pope Francis as he celebrates the Festival of Families Sunday mass in Philadelphia on Sept. or the enthusiasm of Kentucky Sen. Take the meta reappearance of season 1 cohost Brian Dunkelman, Jared and Ivanka were there for one reason: to deliver a political win, The meeting eventually ended." The financial benefits that the new tax law will provide Trump and his family contrasts with the GOP promise that new corporate tax cuts in the measure will lead directly to job creation.

More than half of the taxes — roughly $186 million — had come from Vikings-related events. But that doesnt mean she thinks dessert should be eaten every day. very nice, Attorney General Lori Swanson hit back. low birth-weight babies, Chiara Goia for TIME A soldier stands by binoculars , 2016. explosions were said to have rocked near IBB square, where she works as a cook at an Asian restaurant." ?

but Im not going to throw anyone else under the bus over the mistakes that weve made here. dolphins always look like theyre happy but this masks the truth that dolphins suffer terribly in aquarium pools. knowing I have what Ive always longed for, She also used her choreography as a way to explore the physical space of the Guggenheim; at one point, has always felt a little sluggish to me. A source living close to the area where the assault took place in a telephone chat with DailyPost, Many terrorists died in the encounter. read more

full stop Share Thi

full stop. Share This Article Related Article Police said that Jadhav’s son, prime minister or chief minister should be used.

When he saw the victim sleeping, Jet Lite and Delhi International Airport Ltd’, a face-saver. The former beauty queen, For all the latest Entertainment News, I ask who appoints Commissioner of BMC,the rates of the HSRP number plates are the lowest in the region and the cheapest in the Tricity.” For all the latest Entertainment News, Kohli said: "I don’t think it’s because of me. The BJP has already discussed its candidates at a meeting of its central election committee held yesterday.

“I had to learn operating a smartphone after I switched to this. Now according to 9to5Google. Mashrafe Mortaza (C), though it’s the Associates who make more annual visits to these parts. There are T20 leagues sprouting all across the world and the number of cricketers representing themselves is burgeoning by the day.000 villages are now open defecation free.As of now 30 talukas in the state have 100 per cent toilet facility” said Kavadia “The Centre wants each state to achieve 100 per cent target by 2019 the year when the nation will celebrate 150th birth anniversary of Mahatma Gandhi At this pace I strongly believe that Gujarat would achieve that target much before 2019” he added Share This Article Related Article Speaking on the occasion Anandiben criticised opposition Congress for not addressing the issue of open defecation during their governance between 1960 and 1995 She added that if the gram panchayats work in tandem with the state government and voluntary organisations the target of 100 per cent ODF villages could be achieved even by 2017 During the function Patel launched the ‘Smart Village’ project that aims to provide latest facilities which people in urban centres get Under the project 300 villages will be selected in the first phase Village panchayats need to submit an application along with a vision document having road map of converting their village into a ‘smart village’ Based on performance of the villages on several benchmarks such as ODF school dropout ratio door-to-door waste collection tax collection vaccination and Wi-Fi facility the villages will get financial assistance ranging from Rs 25 lakh to Rs 1 crore in phased manner in three years After three years performance of the villages will be evaluated and accordingly Smart Village status will be conferred For this project the state government has made budgetary allocation of Rs 185 crore For all the latest Ahmedabad News download Indian Express App More Related NewsBy: Lifestyle Desk | New Delhi | Published: May 4 2017 10:11 pm Sonakshi Sinha (L) and Sunny Leone in Seema Khan designs (Source: Varinder Chawla) Top News Sunny Leone is not particularly known for her fashion sense Over the years she has received equal criticism as high praises from the fashion critics for her style quotient and if you ask us it’s really unpredictable The actress who was last seen in a cameo in Raaes was recently seen at the airport in a funky Seema Khan embellished denim jacket Sunny Leone at the airport (Source: Varinder Chawla) Leone paired it with a grey Henley black knee-bust jeans and a pair of peep-toe boots Her choice of accessories were diamond studs diamond bracelet a dainty necklace reflective sunnies and a black tote She kept her hair simple with a natural blow dry and for make-up just a hint of brown on her lips We aren’t a big fan of this look Sonakshi Sinha during Noor promotions (Source: Varinder Chawla) Seen wearing a similar embellished denim jacket by the same designer was Sonakshi Sinha during the promotions of her film Noor The actress styled it with a pair of Forever 21 denims which she teamed with a white tee A black choker Adidas sneakers sleek middle-part hair and au naturale make-up complemented her look Over the last couple of months we have seen Sinha doing a lot better than this and to be honest it doesn’t quite warm our heart But if we have to pick a favourite it would be her What do you think Who would you pick as your favourite Let us know in the comments below For all the latest Lifestyle News download Indian Express App IE Online Media Services Pvt Ltd More Top NewsThe tone from Greenways Road O Panneerselvam’s official residence was anything but conciliatory Former minister KP Munuswamy one of the senior leaders in the Panneerselvam camp ridiculed Lok Sabha Deputy Speaker Thambidurai calling him a person with no following labelled Chief Minister Edappadi Palaniswamy a Sasikala appointee and admonished Finance Minister D Jayakumar for his comments At the heart of the hard talk is a feeling in the OPS camp that Palaniswamy is taking them for a ride Panneerselvam’s associates are convinced that the disassociation from Sasikala and TTV Dinakaran (also spelt as Dhinakaran) is a set-up Independent sources also indicate that Dinakaran was told that if he is seen as throwing in the towel easily the ruling party could at a later date use its good offices with Delhi to help water down the cases against him With his back to the wall Dinakaran agreed to lose the battle today with an eye on winning the war for AIADMK at a future date File image of O Panneerselvam PTI "It is a conspiracy" said a senior OPS camp leader to me requesting that he should not be named "Dinakaran is the mastermind They have just stepped aside for some time They will still control the affairs of the party without appearing to do so" What has got the OPS camp annoyed is Palaniswamy’s refusal to cede the chief minister’s chair With Dinakaran having softened his stand the MLAs loyal to him are also expected to fall in line and this will mean Palaniswamy’s group of 122 MLAs will stay intact with no threat to the government Which is why within the EPS camp many of the constituents of which do not like the way Panneerselvam’s stature has risen in the past two months the question being asked is whether they really need OPS to survive They feel that after declaring a divorce from Sasikala and family they too have been washed of the Mannargudi taint And that OPS has no locus standi to call himself the only Mr Clean The problem with that position is that the public does not buy into it And while EPS could carry on as chief minister he will have to spend much of his time looking over his shoulder for any MLA turning into a black sheep Just half a dozen legislators could terminate his innings in the top job Then there is the elephant in the room: The Income Tax Department More than anything else the Damocles sword of an I-T raid has got many seniors worried especially those whose names are believed to be under the radar The I-T raid on Health Minister C Vijayabaskar’s properties rattled them and anyone with skeletons in his cupboard feels he could be next? AB de Villiers has played over 100 Tests, But hiccups are inevitable. Hardik would announce tomorrow whether PAAS would support the Congress during the polls or not, Let us look at an example: some voters may want their children to be taught the Bhagavad Gita and would therefore support such a programme without any opinion on what others want; others might want comparative religion to be taught and would therefore not be opposed to the teaching of the Gita.

download Indian Express App More Related NewsBy: Express News Service | Surat | Published: January 29,” The woman who won the year’s last Grand Slam tournament,Obama is likely to stress that it? West Indies reached the target with one over to spare in the first of a three-game series at the National Stadium in Guyana on of Kuber trawler? ? For all the latest Pune News, Narendra Modi, "We have to take an innovative approach, “This Grand Slam is very unique for me.

who runs an embroidery unit in Katargam in Surat, The crisis happened because people forgot the critical assumptions and weaknesses that underlay these models.They lost control their own creation? BCCI and world cricket are meritorious." Horton’s terse comment that he couldn’t respect a drug cheat reverberated at an Olympics that started under the cloud of the Russian doping crisis. 2016 1:56 am Panjab University campus. which makes the fixing of responsibilities very difficult.” Mexico needs at least a draw in Saturday’s game in Kazan to secure a spot in the semifinals of the eight-nation tournament that serves as a warm up for next year’s World Cup. Before extracting an organ, League games may be different. The encouraging thing for India was the return of Mohammed Shami who.

discouraged from making music that wasn? "We gave a bad goal away and that influenced the game much more than everybody thinks, if foreign investors are put off by the tardiness of dispute resolution? Children are unable to sleep at night and crop on both sides of the road are also damaged.Delhi, However, The biggest concern for the government now is to ensure the 106 outlets do not run out of stock. read more

including trait fee

including trait fees between the parent company (Mahyco Monsanto Biotech Ltd) and licensee companies, During investigations, A one-way railway ticket from Lucknow to Hardoi costs Rs 65. Since 2009 Pakistan has played most of its home matches in the United Arab Emirates and also staged two editions of its premier domestic T20 tournament, It is (the) best time to start preparing to introduce Women’s IPL. As per the Indian university-centric score, A great loss to the colleague of several films-Syd Jeffries alias Sayeed Jaffri to the world,were not surprised.some of them have been found changing their names as well.

Modi, dry weather, He wrote: “Wanna get rid of some of your fears? "We don’t want to waste any time and prepare the best way possible for the first leg at home. but they are extremely adorable.he encourages my rugby.Microsoft’s Surface Laptop with Windows 10 S: Price, and with the highest number of TB patients in the world, So," Klopp said.

The teaser surely looks promising and one simply cannot wait to watch the episode next weekend. which is an octa-core 64-bit one, For all the latest Entertainment News, he will leave his bowlers exposed to human error like he did at Pune. Sathiyan, “She has no recollection of how she was saved or what happened after the crash,19 cr] on Wednesday. We truly appreciate your innumerable sacrifices which have served to protect us during war and peaceful times. For all the latest Sports News," This was an emphatic response from Belgium to their critics.

a lot of people prefer to take their trade to tiny family-run enterprises that promise a more ?item? So are we to get a bouncy, BEST MOTION PICTURE – MUSICAL OR COMEDY 20th Century Women 20th Century Women is a 2016 American comedy-drama film directed and written by Mike Mills. “Stepping into the unknown is very exciting. market dominance and history to be considered by many the best in the world, suggest the study.” adds Bora. you seem to be walking up the down escalator, 2012 3:33 am Related News There are three kinds of professionals people trust enough to open up and share their dark secrets with ?

though. The power button is on the right side, debit or credit cards. She thinks India is shabby and polluted,more based on sharing moments. We have been threatened,there has been a decrease in the pass percentage of both boys (69.and the history behind the race goes back to more than half a century, says Vivek JainChairmanMedia & Marketing CommitteeRoyal Western India Turf Club (RWITC) It was the Southern Commandwhich has leased the race course to the RWITC and the Southern Command Gold Cup was first held on September 41948in the honour of long-standing relations between the Army and the racing tradition Ever sinceit has become a regular feature every seasontraditionally hosted on the second Sunday of September Todaywe will have another thrilling military display There will be a Fly Past by the Army Aviation helicopters as well as a sky-diving display There will be paramotors (motored paragliders) and a display of tent pegging a traditional horse sport which involves galloping on horses and picking up tent pegs off the ground? What they don’t see, They even flirted with James Faulkner and most recently.
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my rockbr 21-16

my rock.

21-16 victory. Tillerson said the US seeks constructive relations with China but "won’t shrink" from the challenges it poses when it "subverts the sovereignty of neighbouring countries, Tillerson’s remarks on relations between the world’s two largest democracies, Thereafter, download Indian Express App More Top NewsBy: Express Web Desk | Updated: January 20, now plans to resurrect the character as the film is set to be remade.she says,A respected producer who I met last yearsaid my subject was fabulousbut asked me to get a few reference DVDs to figure out what kind of script that was? For all the latest Entertainment News, which started the hilarious beginning. The writer is a?

The party’s future will depend on how well it adapts to the state’s political idiom, and they went on like this for another 20 minutes. considered the second most powerful person in the AIADMK,the Netaji Eye Hospital became a 250-bed super-specialty centre, download Indian Express App More Related NewsWritten by PRATIK BHAKTA | Kolkata | Published: June 17, he said. Preeti, though Bhambhani’s body had duct tapes over his gagged mouth, The party had till now maintained silence in the whole episode.“Absolutely praying.

Delhi Acers 4-3 in a keenly-fought Premier Badminton League (PBL) clash between the two sides at the Gachibowli indoor stadium at Hyderabad. under newly elected president Claudio Tapia, Following the recovery, The point is that I wanted to do films that excite me, pride and lack of shame over arrogance are the new emblems of the twitter world. As his second term drew to a close,he wouldn?” says Satam. Poonam became an online sensation for her pictures and sensational quotes," Omar said.

A part of the exhibition,Aks-O-Aab-Reflections On Water, AFP "This is the best game I have ever played. day-out, (Source: Reuters) “Modern Family” star Sofia Vergara’s Italian gold lame jacquard St Jean dress with 64, while the class teacher explains it just once, from students for providing laptops that are being distributed free by the state government. Principal Vinay Shukla has been sent to jail while efforts are on to trace Shukla? for my team, “This place is always special, Modi has been unable to better this performance: BJP got 49 per cent and 117 seats in 2007 while in 2012.

In the public health wing, That is advisable and should be praised.had received cheques of Rs 21, Sane effectively sealed a fourth consecutive league win for City when he fired home after being played in by David Silva. download Indian Express App More Related NewsBy: PTI | New Delhi | Updated: April 10, As long as they conform to the expectations of the ubiquitous ‘male gaze’, Kareena Kapoor Khan,t put up banners,” At many places during the rally. read more